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Chemistry

Chemistry
Asymmetric Synthesis Chiral Auxiliaries Chiral Building Blocks Chiral Catalysts, Chiral Ligands and Chiral Reagents Chiral Resolution Reagents
Catalysis Chemistry C-H Activation Carbon-Donor Ligands Cross-Coupling Cross-Coupling using Transition Metal Catalysts Diketone Ligands Hydrogenation Main-Group Elements Metal Catalysts Nitrogen-Donor Ligands Non-Precious Metal Catalysts Olefin Ligands Olefin Metathesis Organocatalysts Other Ligands Phosphorous Compounds Photocatalysts Rare-Earth Elements Transition Elements
Chemical Biology Conjugation Chemistry Glycoscience Linkers and Crosslinkers Nucleic Acid Chemistry PEGylation Peptide Chemistry Photolabile Protecting Group
Heterocyclic Building Blocks Acridines Aliphatic Heterocycles Aromatic Heterocycles Azetidines Benzimidazoles Benzisoxazoles Benzodioxans Benzofurans Benzothiazoles Benzothiophenes Benzoxazoles Carbazoles Cinnolines Dioxolanes Dioxoles Epoxides Furans Halogenated Heterocycles Heterocyclic Building Block Imidazoles Imidazolidines Imidazolines Indazoles Indoles More >>
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Synthetic Reagents Acids & Bases C-C Bond Formation C-X Bond Formation (Halogen) C-X Bond Formation (Non-Halogen) Chelation and Complexation Compounds Condensation Agents Coupling Dehydrating Reagents Fluorination Reagents Halogenation Reagents Hypervalent Iodine Compounds Inorganic Salts Oxidizing Agents Phase Transfer Catalysts Polymer-Supported Reagents Protection, Deprotection and Derivatization Radical Chemsitry Reduction Synthetic Reagent Others Wittig Reagents

Pharmaceutical Intermediates

Pharmaceutical Intermediates
Analgesics Benzhydrocodone Bicifadine Debio-0827 Parecoxib Pregnanolone Spiradoline Tapentadol Zucapsaicin related
Anesthetics Fospropofol Levobupivacaine Remimazolam Remimazolam besylate Ropivacaine
Anti-Addiction Agents Kakonein Varenicline
Anti-inflammatory Agents ATB-346 related Balsalazide Celecoxib related Dilmapimod Esflurbiprofen Etoricoxib Filgotinib related Flobufen Grapiprant related GW-406381 Imrecoxib related Licofelone related Lumiracoxib Meloxicam related Mesalazine Naproxcinod Polmacoxib Rofecoxib related Zidometacin
Antibacterials AFN-1252 related Alatrofloxacin Besifloxacin Brilacidin Cefilavancin Ceftaroline Fosamil Ceftizoxime alapivoxil Cethromycin related Daptomycin related Delafloxacin related Eravacycline related Ertapenem related Finafloxacin related Garenoxacin Gemifloxacin related Grepafloxacin related Iseganan Levonadifloxacin LFF 571 Linezolid related Morinidazole related Moxifloxacin related Nemonoxacin Omadacycline related More >>
Anticonvulsants Brivaracetam Eslicarbazepine Acetate related Gabapentin Enacarbil JNJ-10234094 Levetiracetam related Losigamone Naluzotan Perampanel Pregabalin Remacemide Retigabine/Ezogabine Rufinamide Tiagabine related
Antidementia Agents Azeliragon related Davunetide Donepezil related Ensaculin Idalopirdine Lanabecestat NTC-942 SB 742457 Semagacestat related T-807 Verubecestat related VX 745
Antidepressants 4-Chlorokynurenine Agomelatine related Allopregnanolone related Amibegron Amitifadine Aripiprazole related Basimglurant Befloxatone Befuraline Desvenlafaxine related Duloxetine Escitalopram related Esketamine Fengabine Fluparoxan Gepirone Levomilnacipran MK-0657 Quetiapine Rapastinel related Sunipetron Vilazodone Vortioxetine related Wf-516
Antiemetics Aprepitant related Dolasetron related Fosaprepitant related Palonosetron related Rolapitant related
Antifungals Anidulafungin related Caspofungin Eberconazole Efinaconazole related G1 Isavuconazonium Sulfate related Luliconazole related Micafungin related MK 3118 Posaconazole related Sertaconazole Tavaborole Voriconazole VT-1161
Antigout Agents Arhalofenate Febuxostat related Topiroxostat related
Antimigraine Agents Dotarizine Eletriptan related Frovatriptan related Lasmiditan related Rizatriptan related Telcagepant related Ubrogepant related


Antineoplastics Abemaciclib related Abiraterone Acetate related Acadesine Acalabrutinib related Acelarin related Afatinib Afuresertib related Aldoxorubicin Alectinib related Alisertib related Alpelisib related AMG-232 related Amifostine Anamorelin related Anastrozole Apalutamide Apatinib related Apaziquone AR-42 related Arzoxifene ASLAN-002 Asoprisnil related AT-7519 Axitinib related More >>
Antiparasitics AQ-13 Artefenomel related Artemisone Fexinidazole related Nitazoxanide related Phenothrin related Tafenoquine related
Antiparkinson Agents Dipraglurant related Entacapone related Etilevodopa Istradefylline related Lazabemide Opicapone related Pramipexole related Rasagiline related Rivastigmine related Ropinirole related Rotigotine Safinamide related Sarizotan Tolcapone related Tozadenant related
Antipsychotics Ampalex related Aripiprazole Lauroxil related Asenapine related Bitopertin related BL-1020 Blonanserin BMY-14802-1 Brexpiprazole related Cariprazine related Encenicline Erteberel Iloperidone ITI-007 Lurasidone Neboglamine Olanzapine related Paliperidone related Perospirone Pimavanserin related Raclopride Risperidone Ziprasidone
Antispasticity Agents Arbaclofen
Antivirals Abacavir related Adefovir Dipivoxil related Apricitabine Asunaprevir related Atazanavir related Atevirdine Beclabuvir related BIT-225 BMS-955176 Boceprevir Brincidofovir Cabotegravir related Cidofovir Clevudine related Cobicistat related Daclatasvir related Darunavir related Dasabuvir Delavirdine related Deleobuvir Dolutegravir Doravirine related Efavirenz related Elbasvir related More >>
Anxiolytics Bretazenil Enciprazine Glemanserin Osemozotan Saredutant Zatosetron
Blood Glucose Regulators Alogliptin related AMG-131 Free Anagliptin related Balaglitazone related Bexagliflozin related Canagliflozin CS-038 Free Dapagliflozin related Denagliptin related Dutogliptin related Empagliflozin related Ertugliflozin Evogliptin related Fasiglifam Gemigliptin related Glimepiride related GSK-2330672 Ipragliflozin related Lacosamide Linagliptin related Lobeglitazone Luseogliflozin related Melogliptin Miglitol related More >>
Blood Products Anagrelide related Apixaban related Ataciguat related Avatrombopag related Avoralstat Azacitidine Betrixaban related CCX-168 Dabigatran Etexilate related Danegaptide Disufenton Edoxaban related Eltrombopag related Flindokalner Fostamatinib related Idrabiotaparinux Lefradafiban Lubeluzole Lusutrombopag related Momelotinib Neu-2000 Orbofiban related Rivaroxaban related Rivipansel related More >>
Cardiovascular Agents Aliskiren related Allisartan Isoproxil Arbutamine Atorvastatin related Atrasentan related Avanafil Azilsartan Medoxomil related Azilsartan related Azimilide related Bempedoic acid Binodenoson Candesartan related Cangrelor related Choline Fenofibrate Clevidipine Butyrate Conivaptan related Dalcetrapib related Darapladib related Darodipine Dofetilide Dronedarone related Eplerenone related Eprosartan related Evacetrapib related More >>
CNS Agents ALKS-8700 Arimoclomol Atomoxetine Dalfampridine Dexmethylphenidate Edivoxetine Fingolimod related Gaboxadol Laquinimod related Ponesimod related Teriflunomide related
Dental & Oral Agents Honokiol related


Dermatological Agents Asimadoline Benvitimod related Bepotastine Crisaborole Omiganan Orvepitant Ozenoxacin PAC 14028 Pefcalcitol Tazarotene Tradipitant related TU-2100 UR-1505
Electrolytes Carglumic Acid Deferasirox related Tolvaptan related
Gastrointestinal Agents Acotiamide Alvimopan related Bevenopran Cilansetron Dalcotidine Dexlansoprazole Dexloxiglumide Eluxadoline Emoxipine Esomeprazole related Glycopyrronium Bromide Ibandronate related Ibandronic Acid Ibodutant Lubiprostone related Naloxegol related Pantoprazole related Prucalopride related Rabeprazole related Racecadotril related Relamorelin Renzapride Revaprazan Rotraxate More >>
Genetic/Enzyme Disorder Eliglustat Glycerol phenylbutyrate Miglustat related Obeticholic Acid
Genitourinary Agents Alfuzosin related Antofloxacin Dapoxetine related Darifenacin related Dutasteride related Fesoterodine Flibanserin related Imidafenacin related Inaperisone Mirabegron related Ospemifene related Prasterone Sildenafil related Solabegron Solifenacin related Tadalafil related Tolterodine Ulipristal Acetate related Vibegron
Immunological Agents AJM-300 APD-334 Apremilast Baricitinib related Darbufelone Decernotinib related FK-3311 Icatibant related Iguratimod related KRP-203 related Leniolisib related Mycophenolate Mofetil related Mycophenolate Sodium Ozanimod Ridogrel Solupred Tofacitinib
Metabolic Bone Disease Doxercalciferol related Etelcalcetide related Maxacalcitol related Risedronic Acid
Ophthalmic Agents Alcaftadine related Bimatoprost related Brinzolamide related Diquafosol related Emixustat related Icoduline Latanoprost Latanoprostene bunod Levobetaxolol related Lifitegrast Nepafenac related Netarsudil NS-2 Omidenepag Isopropyl Ripasudil Travoprost related
Respiratory Tract Aclidinium Bromide related Ambrisentan related Arformoterol Bedaquiline Bosentan related Broxaterol Ciclesonide related Delamanid related Fluticasone Furoate Foropafant Fudosteine related Ivacaftor related Lumacaftor Macitentan Masilukast Methylprednisolone OC000459 related Olodaterol Pirfenidone related Presatovir related Riociguat Roflumilast related Selexipag Sinapultide More >>
Skeletal Muscle Relaxants Cisatracurium Besylate related
Sleep Disorder Agents Adipiplon Almorexant related Armodafinil Eplivanserin Indiplon related JNJ-42847922 Lemborexant related Pitolisant related R-228060 Ramelteon Suvorexant Tasimelteon related Zaleplon

Inhibitors/Agonists

Inhibitors/Agonists
ADCs ADC Linker ADC Linker with Payload
Anti-infection Antibacterial Antifungal Antiparasitic CCR CMV dengue virus Filovirus HBV HCV HIV HIV Integrase HIV Protease HRV HSV Influenza Virus NNRTI NRTI Orthopoxvirus Reverse Transcriptase RSV SARS-CoV SQLE
Apoptosis Apoptosis Inducer Bcl-2 c-Myc c-RET Caspase DAPK FAS G-quadruplex IAP MDM2 p53 PD-1/PD-L1 PERK PKD RIP Kinase Survivin Thymidylate Synthase TNF-alpha
Autophagy Cell Autophagy CXCR LRRK2 MLK SPHK ULK
Biochemical Reagent Intermediate and Others
Biochemical Reagents Biochemical Assay Reagent Dye Reagent Intermidate and Others
Cell Cycle ADC Toxin APC Aurora Kinase c-Myc Casein Kinase CDK Chk CRM1 DHFR DNA/RNA Synthesis FOX G-quadruplex Haspin Kinase KLF LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p21 PAK PD-1/PD-L1 PERK PLK PPAR More >>
Cytoskeleton Akt Arp2/3 Complex Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK PKC Wnt β-catenin
DNA Damage ATM/ATR DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis HDAC MTH1 PARP RAD51 Sirtuin Telomerase Topoisomerase
Endocrinology/Hormones 5 Alpha Reductase ACE Adiponectin Receptor Androgen Receptor Angiotensin Receptor Aromatase ERR GHSR Glucocorticoid Receptor GNRH Receptor GPCR Neprilysin Neuropeptide Y receptor Opioid Receptor OXTR Progesterone Receptor prolactin Renin TSH Receptor
Epigenetics Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP Pim Sirtuin
GPCR/G Protein Adenosine Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor cAMP cAMP related Cannabinoid Receptor CaSR Cholecystokinin Receptor CRF receptor Endothelin Receptor GHSR Glucagon Receptor GNRH Receptor Gsα Guanylate Cyclase LPA Receptor LPL Receptor Motilin Receptor Neuropeptide Y receptor Neurotensin Receptor NMUR Opioid Receptor OX Receptor More >>


Immunology/Inflammation Arginase CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTA4H LTR MALT1 MyD88 NADPH Oxidase NF-κB NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK More >>
JAK/STAT Signaling EGFR FLT3 JAK Pim STAT
MAPK/ERK Pathway ERK JNK MEK MLK MNK p38 MAPK Raf RSK ZAK
Membrane Transporter/Ion Channel AChR AMPAR ATPase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel EAAT2 GABA Receptor GlyT1 HCN Channel MAT MCT Membrane Transporter/Ion Channel Na+/Ca2+ Exchanger Na+/K+ ATPase NBC NKCC NMDAR Oct P-gp P2X Receptor Potassium Channel More >>
Metabolic Enzyme 15-PGDH 2OG oxygenases 5 Alpha Reductase ACC ACE Adenosine Deaminase Adenosine Kinase Adenosine Receptor Adenosylhomocysteinase AhR ALDH Aldose Reductase Aminopeptidase Arginase ATP Citrate Lyase ATP synthase Carbonic Anhydrase Cathepsin CETP COMT CPA CYP51 Decarboxylase Dehydrogenase More >>
Natural Product
Natural Products Alkaloids Cerebrosides Chalcones Coumarins Diterpenoids Flavonoids Iridoids Lignans Lipids Miscellaneous Monoterpenoids Naphthols Nature Product Other Natural Product Other Terpenoids Phenols Phenylpropanoids Quinones Saccharides Sesquiterpenoids Tetraterpenoids Thiophenes Triterpenoids Xanthones
Neuronal Signaling 5-HT Receptor AChE AChR Adrenergic Receptor AMPAR Amyloid-β CaMK Cannabinoid Receptor CGRP Receptor DAT Dopamine Receptor enkephalinase GABA Receptor glucosylceramide synthase Imidazoline Receptor mGluR MT Receptor NET NK Receptor NMDAR Opioid Receptor OXTR ryanodine receptor-1 SERT More >>
NF-κB IKK NF-κB NOD1 RIP Kinase TAK1
Other Inhibitors CD73 GBF1 hCAR histidine kinase MTTP Other Targets Others PEPT Phosphatase PNP PXR RasGAP Rev-ErbA serine hydrolase SQS TNK VDA XOR
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI3K Autophagy PI4K PIKfyve PTEN RSK SRPK
Protease aspartic protease Caspase Cathepsin Cysteine Protease DPP4 Glutaminase HIV Protease MMP PAI-1 PE Proteasome Secretase Ser/Thr Protease Tyrosinase

Material Science

Material Science
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HomeInhibitors/AgonistsJAK/STAT SignalingEGFR

EGFR

Filters

EGFR

(2-Fluoro-3-methoxy-5-methylphenyl)boronic acid

5g650.0 USD

(2-Fluoro-3-methoxy-5-methylphenyl)boronic acid

2096329-52-9

PD158780

25mg287.0 USD

171179-06-9

WZ3146

1mg56.0 USD

1214265-56-1

Daphnetin

100mg43.0 USD

486-35-1

PD168393

50mg277.0 USD

194423-15-9

EGF816

10mg165.0 USD

1508250-71-2

Poziotinib

10mg131.0 USD

1092364-38-9

CL-387785

100mg287.0 USD

194423-06-8

TAK-285

10mg269.0 USD

871026-44-7

ARRY-380Analog

25mg247.0 USD

ARRY-380Analog

937265-83-3

CNX-2006

100mg861.0 USD

1375465-09-0

AZD3759

5mg60.0 USD

1626387-80-1

Mutated EGFR-IN-1

100mg755.0 USD

Mutated EGFR-IN-1

1421372-66-8

4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline

25g199.0 USD

4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline

183321-74-6

Canertinib

10mg58.0 USD

267243-28-7

AV-412 Tosylate

5mg111.0 USD

AV-412 Tosylate

451493-31-5

WHI-P180

250mg149.0 USD

211555-08-7

Dacomitinib

50mg229.0 USD

Dacomitinib

1110813-31-4

CO-1686

100mg194.0 USD

1374640-70-6

Osimertinib

25g931.0 USD

Osimertinib

1421373-65-0

AZD9291 Mesylate

250mg60.0 USD

AZD9291 Mesylate

1421373-66-1

PD153035

5g958.0 USD

153436-54-5

AG-1478

5g1159.0 USD

153436-53-4

Olmutinib

1mg23.0 USD

1353550-13-6

MutantEGFRinhibitor

25mg845.0 USD

MutantEGFRinhibitor

1421373-62-7

CO-1686 hydrobromide

50mg172.0 USD

CO-1686 hydrobromide

1446700-26-0

EGF816 mesylate

50mg1444.0 USD

EGF816 mesylate

1508250-72-3

WHI-P180 hydrochloride

5mg239.0 USD

WHI-P180 hydrochloride

153437-55-9

Lapatinib ditosylate

5g534.0 USD

Lapatinib ditosylate

388082-77-7

WZ4002

100mg338.0 USD

1213269-23-8

AV-412

2mg120.0 USD

451492-95-8

Gefitinibhydrochloride

10g297.0 USD

Gefitinibhydrochloride

184475-55-6

XL647

10mg588.0 USD

781613-23-8

Erlotinib mesylate

250mg90.0 USD

Erlotinib mesylate

248594-19-6

Neratinib

5mg50.0 USD

698387-09-6

Erlotinib Hydrochloride

1g12.0 USD

Erlotinib Hydrochloride

183319-69-9

Icotinib

5mg68.0 USD

610798-31-7

AC480

10mg96.0 USD

714971-09-2

OSI-420

1mg53.0 USD

183320-51-6

Cyasterone

10mg67.0 USD

17086-76-9

BMS-599626 Hydrochloride

5mg91.0 USD

BMS-599626 Hydrochloride

873837-23-1

WZ8040

10mg206.0 USD

1214265-57-2

BMS-690514

100mg425.0 USD

859853-30-8

AST-1306

50mg811.0 USD

897383-62-9

Avitinib

25mg124.0 USD

1557267-42-1

Avitinib Maleate

10mg131.0 USD

Avitinib Maleate

1557268-88-8

EAI045

250mg96.0 USD

1942114-09-1

Lapatinib ditosylate hydrate

50mg67.0 USD

Lapatinib ditosylate hydrate

388082-78-8

BIBX 1382

100mg453.0 USD

196612-93-8

AZ5104

10mg88.0 USD

1421373-98-9

Products(64) Items 1-0 of 2

(2-Fluoro-3-methoxy-5-methylphenyl)boronic acid

5g650.0 USD

(2-Fluoro-3-methoxy-5-methylphenyl)boronic acid

2096329-52-9

PD158780

25mg287.0 USD

171179-06-9

WZ3146

1mg56.0 USD

1214265-56-1

Daphnetin

100mg43.0 USD

486-35-1

PD168393

50mg277.0 USD

194423-15-9

EGF816

10mg165.0 USD

1508250-71-2

Poziotinib

10mg131.0 USD

1092364-38-9

CL-387785

100mg287.0 USD

194423-06-8

TAK-285

10mg269.0 USD

871026-44-7

ARRY-380Analog

25mg247.0 USD

ARRY-380Analog

937265-83-3

CNX-2006

100mg861.0 USD

1375465-09-0

AZD3759

5mg60.0 USD

1626387-80-1

Mutated EGFR-IN-1

100mg755.0 USD

Mutated EGFR-IN-1

1421372-66-8

4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline

25g199.0 USD

4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline

183321-74-6

Canertinib

10mg58.0 USD

267243-28-7

AV-412 Tosylate

5mg111.0 USD

AV-412 Tosylate

451493-31-5

WHI-P180

250mg149.0 USD

211555-08-7

Dacomitinib

50mg229.0 USD

Dacomitinib

1110813-31-4

CO-1686

100mg194.0 USD

1374640-70-6

Osimertinib

25g931.0 USD

Osimertinib

1421373-65-0

AZD9291 Mesylate

250mg60.0 USD

AZD9291 Mesylate

1421373-66-1

PD153035

5g958.0 USD

153436-54-5

AG-1478

5g1159.0 USD

153436-53-4

Olmutinib

1mg23.0 USD

1353550-13-6

MutantEGFRinhibitor

25mg845.0 USD

MutantEGFRinhibitor

1421373-62-7

CO-1686 hydrobromide

50mg172.0 USD

CO-1686 hydrobromide

1446700-26-0

EGF816 mesylate

50mg1444.0 USD

EGF816 mesylate

1508250-72-3

WHI-P180 hydrochloride

5mg239.0 USD

WHI-P180 hydrochloride

153437-55-9

Lapatinib ditosylate

5g534.0 USD

Lapatinib ditosylate

388082-77-7

WZ4002

100mg338.0 USD

1213269-23-8

AV-412

2mg120.0 USD

451492-95-8

Gefitinibhydrochloride

10g297.0 USD

Gefitinibhydrochloride

184475-55-6

XL647

10mg588.0 USD

781613-23-8

Erlotinib mesylate

250mg90.0 USD

Erlotinib mesylate

248594-19-6

Neratinib

5mg50.0 USD

698387-09-6

Erlotinib Hydrochloride

1g12.0 USD

Erlotinib Hydrochloride

183319-69-9

Icotinib

5mg68.0 USD

610798-31-7

AC480

10mg96.0 USD

714971-09-2

OSI-420

1mg53.0 USD

183320-51-6

Cyasterone

10mg67.0 USD

17086-76-9

BMS-599626 Hydrochloride

5mg91.0 USD

BMS-599626 Hydrochloride

873837-23-1

WZ8040

10mg206.0 USD

1214265-57-2

BMS-690514

100mg425.0 USD

859853-30-8

AST-1306

50mg811.0 USD

897383-62-9

Avitinib

25mg124.0 USD

1557267-42-1

Avitinib Maleate

10mg131.0 USD

Avitinib Maleate

1557268-88-8

EAI045

250mg96.0 USD

1942114-09-1

Lapatinib ditosylate hydrate

50mg67.0 USD

Lapatinib ditosylate hydrate

388082-78-8

BIBX 1382

100mg453.0 USD

196612-93-8

AZ5104

10mg88.0 USD

1421373-98-9

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