(Neprilysin) | BLDpharm

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Chemistry

Chemistry
Asymmetric Synthesis Chiral Auxiliaries Chiral Building Blocks Chiral Catalysts, Chiral Ligands and Chiral Reagents Chiral Resolution Reagents
Catalysis Chemistry C-H Activation Carbon-Donor Ligands Cross-Coupling Cross-Coupling using Transition Metal Catalysts Diketone Ligands Hydrogenation Main-Group Elements Metal Catalysts Nitrogen-Donor Ligands Non-Precious Metal Catalysts Olefin Ligands Olefin Metathesis Organocatalysts Other Ligands Phosphorous Compounds Photocatalysts Rare-Earth Elements Transition Elements
Chemical Biology Conjugation Chemistry Glycoscience Linkers and Crosslinkers Nucleic Acid Chemistry PEGylation Peptide Chemistry Photolabile Protecting Group
Heterocyclic Building Blocks Acridines Aliphatic Heterocycles Aromatic Heterocycles Azetidines Benzimidazoles Benzisoxazoles Benzodioxans Benzofurans Benzothiazoles Benzothiophenes Benzoxazoles Carbazoles Cinnolines Dioxolanes Dioxoles Epoxides Furans Halogenated Heterocycles Heterocyclic Building Block Imidazoles Imidazolidines Imidazolines Indazoles Indoles More >>
Organic Building Blocks Acyl Chlorides Alcohols Aldehydes Aliphatic Chain Hydrocarbons Aliphatic Cyclic Hydrocarbons Aliphatic Hydrocarbons Alkenyls Alkyls Alkynyls Amides Amidines Amines Anhydrides Aryls Azides Azoes Benzyl Chlorides Bromides Carboxylic Acid Salts Carboxylic Acids Chlorides Diazoes Difluoromethyls Esters More >>
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Specialty Synthesis Enzyme-Mediated Synthesis Fluorous Synthesis Ionic Liquids Solid Supported Synthesis
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Synthetic Reagents Acids & Bases C-C Bond Formation C-X Bond Formation (Halogen) C-X Bond Formation (Non-Halogen) Chelation and Complexation Compounds Condensation Agents Coupling Dehydrating Reagents Fluorination Reagents Halogenation Reagents Hypervalent Iodine Compounds Inorganic Salts Oxidizing Agents Phase Transfer Catalysts Polymer-Supported Reagents Protection, Deprotection and Derivatization Radical Chemsitry Reduction Synthetic Reagent Others Wittig Reagents

Pharmaceutical Intermediates

Pharmaceutical Intermediates
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Antidementia Agents Azeliragon related Davunetide Donepezil related Ensaculin Idalopirdine Lanabecestat NTC-942 SB 742457 Semagacestat related T-807 Verubecestat related VX 745
Antidepressants 4-Chlorokynurenine Agomelatine related Allopregnanolone related Amibegron Amitifadine Aripiprazole related Basimglurant Befloxatone Befuraline Desvenlafaxine related Duloxetine Escitalopram related Esketamine Fengabine Fluparoxan Gepirone Levomilnacipran MK-0657 Quetiapine Rapastinel related Sunipetron Vilazodone Vortioxetine related Wf-516
Antiemetics Aprepitant related Dolasetron related Fosaprepitant related Palonosetron related Rolapitant related
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Antineoplastics Abemaciclib related Abiraterone Acetate related Acadesine Acalabrutinib related Acelarin related Afatinib Afuresertib related Aldoxorubicin Alectinib related Alisertib related Alpelisib related AMG-232 related Amifostine Anamorelin related Anastrozole Apalutamide Apatinib related Apaziquone AR-42 related Arzoxifene ASLAN-002 Asoprisnil related AT-7519 Axitinib related More >>
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Antipsychotics Ampalex related Aripiprazole Lauroxil related Asenapine related Bitopertin related BL-1020 Blonanserin BMY-14802-1 Brexpiprazole related Cariprazine related Encenicline Erteberel Iloperidone ITI-007 Lurasidone Neboglamine Olanzapine related Paliperidone related Perospirone Pimavanserin related Raclopride Risperidone Ziprasidone
Antispasticity Agents Arbaclofen
Antivirals Abacavir related Adefovir Dipivoxil related Apricitabine Asunaprevir related Atazanavir related Atevirdine Beclabuvir related BIT-225 BMS-955176 Boceprevir Brincidofovir Cabotegravir related Cidofovir Clevudine related Cobicistat related Daclatasvir related Darunavir related Dasabuvir Delavirdine related Deleobuvir Dolutegravir Doravirine related Efavirenz related Elbasvir related More >>
Anxiolytics Bretazenil Enciprazine Glemanserin Osemozotan Saredutant Zatosetron
Blood Glucose Regulators Alogliptin related AMG-131 Free Anagliptin related Balaglitazone related Bexagliflozin related Canagliflozin CS-038 Free Dapagliflozin related Denagliptin related Dutogliptin related Empagliflozin related Ertugliflozin Evogliptin related Fasiglifam Gemigliptin related Glimepiride related GSK-2330672 Ipragliflozin related Lacosamide Linagliptin related Lobeglitazone Luseogliflozin related Melogliptin Miglitol related More >>
Blood Products Anagrelide related Apixaban related Ataciguat related Avatrombopag related Avoralstat Azacitidine Betrixaban related CCX-168 Dabigatran Etexilate related Danegaptide Disufenton Edoxaban related Eltrombopag related Flindokalner Fostamatinib related Idrabiotaparinux Lefradafiban Lubeluzole Lusutrombopag related Momelotinib Neu-2000 Orbofiban related Rivaroxaban related Rivipansel related More >>
Cardiovascular Agents Aliskiren related Allisartan Isoproxil Arbutamine Atorvastatin related Atrasentan related Avanafil Azilsartan Medoxomil related Azilsartan related Azimilide related Bempedoic acid Binodenoson Candesartan related Cangrelor related Choline Fenofibrate Clevidipine Butyrate Conivaptan related Dalcetrapib related Darapladib related Darodipine Dofetilide Dronedarone related Eplerenone related Eprosartan related Evacetrapib related More >>
CNS Agents ALKS-8700 Arimoclomol Atomoxetine Dalfampridine Dexmethylphenidate Edivoxetine Fingolimod related Gaboxadol Laquinimod related Ponesimod related Teriflunomide related
Dental & Oral Agents Honokiol related


Dermatological Agents Asimadoline Benvitimod related Bepotastine Crisaborole Omiganan Orvepitant Ozenoxacin PAC 14028 Pefcalcitol Tazarotene Tradipitant related TU-2100 UR-1505
Electrolytes Carglumic Acid Deferasirox related Tolvaptan related
Gastrointestinal Agents Acotiamide Alvimopan related Bevenopran Cilansetron Dalcotidine Dexlansoprazole Dexloxiglumide Eluxadoline Emoxipine Esomeprazole related Glycopyrronium Bromide Ibandronate related Ibandronic Acid Ibodutant Lubiprostone related Naloxegol related Pantoprazole related Prucalopride related Rabeprazole related Racecadotril related Relamorelin Renzapride Revaprazan Rotraxate More >>
Genetic/Enzyme Disorder Eliglustat Glycerol phenylbutyrate Miglustat related Obeticholic Acid
Genitourinary Agents Alfuzosin related Antofloxacin Dapoxetine related Darifenacin related Dutasteride related Fesoterodine Flibanserin related Imidafenacin related Inaperisone Mirabegron related Ospemifene related Prasterone Sildenafil related Solabegron Solifenacin related Tadalafil related Tolterodine Ulipristal Acetate related Vibegron
Immunological Agents AJM-300 APD-334 Apremilast Baricitinib related Darbufelone Decernotinib related FK-3311 Icatibant related Iguratimod related KRP-203 related Leniolisib related Mycophenolate Mofetil related Mycophenolate Sodium Ozanimod Ridogrel Solupred Tofacitinib
Metabolic Bone Disease Doxercalciferol related Etelcalcetide related Maxacalcitol related Risedronic Acid
Ophthalmic Agents Alcaftadine related Bimatoprost related Brinzolamide related Diquafosol related Emixustat related Icoduline Latanoprost Latanoprostene bunod Levobetaxolol related Lifitegrast Nepafenac related Netarsudil NS-2 Omidenepag Isopropyl Ripasudil Travoprost related
Respiratory Tract Aclidinium Bromide related Ambrisentan related Arformoterol Bedaquiline Bosentan related Broxaterol Ciclesonide related Delamanid related Fluticasone Furoate Foropafant Fudosteine related Ivacaftor related Lumacaftor Macitentan Masilukast Methylprednisolone OC000459 related Olodaterol Pirfenidone related Presatovir related Riociguat Roflumilast related Selexipag Sinapultide More >>
Skeletal Muscle Relaxants Cisatracurium Besylate related
Sleep Disorder Agents Adipiplon Almorexant related Armodafinil Eplivanserin Indiplon related JNJ-42847922 Lemborexant related Pitolisant related R-228060 Ramelteon Suvorexant Tasimelteon related Zaleplon

Inhibitors/Agonists

Inhibitors/Agonists
ADCs ADC Linker ADC Linker with Payload
Anti-infection Antibacterial Antifungal Antiparasitic CCR CMV dengue virus Filovirus HBV HCV HIV HIV Integrase HIV Protease HRV HSV Influenza Virus NNRTI NRTI Orthopoxvirus Reverse Transcriptase RSV SARS-CoV SQLE
Apoptosis Apoptosis Inducer Bcl-2 c-Myc c-RET Caspase DAPK FAS G-quadruplex IAP MDM2 p53 PD-1/PD-L1 PERK PKD RIP Kinase Survivin Thymidylate Synthase TNF-alpha
Autophagy Autophagy CXCR LRRK2 MLK SPHK ULK
Biochemical Reagent Intermediate and Others
Biochemical Reagents Biochemical Assay Reagent Dye Reagent Intermidate and Others
Cell Cycle ADC Toxin APC Aurora Kinase c-Myc Casein Kinase CDK Chk CRM1 DHFR DNA/RNA Synthesis FOX G-quadruplex Haspin Kinase KLF LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p21 PAK PD-1/PD-L1 PERK PLK PPAR More >>
Cytoskeleton Akt Arp2/3 Complex Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK PKC Wnt β-catenin
DNA Damage ATM/ATR DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis HDAC MTH1 PARP RAD51 Sirtuin Telomerase Topoisomerase
Endocrinology/Hormones 5 Alpha Reductase ACE Adiponectin Receptor Androgen Receptor Angiotensin Receptor Aromatase ERR GHSR Glucocorticoid Receptor GNRH Receptor GPCR Neprilysin Neuropeptide Y receptor Opioid Receptor OXTR Progesterone Receptor prolactin Renin TSH Receptor
Epigenetics Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP Pim Sirtuin
GPCR/G Protein Adenosine Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor cAMP cAMP related Cannabinoid Receptor CaSR Cholecystokinin Receptor CRF receptor Endothelin Receptor GHSR Glucagon Receptor GNRH Receptor Gsα Guanylate Cyclase LPA Receptor LPL Receptor Motilin Receptor Neuropeptide Y receptor Neurotensin Receptor NMUR Opioid Receptor OX Receptor More >>


Immunology/Inflammation Arginase CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTA4H LTR MALT1 MyD88 NADPH Oxidase NF-κB NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK More >>
JAK/STAT Signaling EGFR FLT3 JAK Pim STAT
MAPK/ERK Pathway ERK JNK MEK MLK MNK p38 MAPK Raf RSK ZAK
Membrane Transporter/Ion Channel AChR AMPAR ATPase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel EAAT2 GABA Receptor GlyT1 HCN Channel MAT MCT Membrane Transporter/Ion Channel Na+/Ca2+ Exchanger Na+/K+ ATPase NBC NKCC NMDAR Oct P-gp P2X Receptor Potassium Channel More >>
Metabolic Enzyme 15-PGDH 2OG oxygenases 5 Alpha Reductase ACC ACE Adenosine Deaminase Adenosine Kinase Adenosine Receptor Adenosylhomocysteinase AhR ALDH Aldose Reductase Aminopeptidase Arginase ATP Citrate Lyase ATP synthase Carbonic Anhydrase Cathepsin CETP COMT CPA CYP51 Decarboxylase Dehydrogenase More >>
Natural Product
Natural Products Alkaloids Cerebrosides Chalcones Coumarins Diterpenoids Flavonoids Iridoids Lignans Lipids Miscellaneous Monoterpenoids Naphthols Nature Product Other Natural Product Other Terpenoids Phenols Phenylpropanoids Quinones Saccharides Sesquiterpenoids Tetraterpenoids Thiophenes Triterpenoids Xanthones
Neuronal Signaling 5-HT Receptor AChE AChR Adrenergic Receptor AMPAR Amyloid-β CaMK Cannabinoid Receptor CGRP Receptor DAT Dopamine Receptor enkephalinase GABA Receptor glucosylceramide synthase Imidazoline Receptor mGluR MT Receptor NET NK Receptor NMDAR Opioid Receptor OXTR ryanodine receptor-1 SERT More >>
NF-κB IKK NF-κB NOD1 RIP Kinase TAK1
Other Inhibitors CD73 GBF1 hCAR histidine kinase MTTP Other Targets Others PEPT Phosphatase PNP PXR RasGAP Rev-ErbA serine hydrolase SQS TNK VDA XOR
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI3K Autophagy PI4K PIKfyve PTEN RSK SRPK
Protease aspartic protease Caspase Cathepsin Cysteine Protease DPP4 Glutaminase HIV Protease MMP PAI-1 PE Proteasome Secretase Ser/Thr Protease Tyrosinase

Material Science

Material Science
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Magnetic Materials Magnetic Ionic Liquids Magnetic Material Magnetic Metal Complexes Organic Radicals
Material Building Blocks Ligands for Functional Metal Complexes Liquid Crystal (LC) Building Blocks Phthalocyanine Building Blocks Polymer and Macromolecule Semiconductor Building Blocks Small Molecule Semiconductor Building Blocks Solubility Enhancing Reagents Supramolecular Host Materials
Material Others Mateial Other
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Organic Pigments Organic Pigment
Polymer Science Monomers Polymer Additives Polymerization Reagents Polymers Resins

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